Artificial Intelligence at Weill School of Veterinary Medicine
Researchers at the UC Davis Weill School of Veterinary Medicine are applying artificial intelligence and machine learning to questions in animal health, human health, food safety, and agricultural production.
AI and machine learning research at Weill SVM brings together expertise from across UC Davis. Published collaborations connect veterinary medicine with computer science, mathematics, animal science, and pediatrics, alongside the MIND Institute and Center for Mind and Brain. These partnerships combine computational methods with clinical and biological expertise to investigate disease risks, analyze biomedical images, and understand complex biological systems.
Explore our research areas and selected publications below. Each entry includes the complete author list and a link to the publication. WSVM-affiliated (or affiliated at time of publication) authors are shown in bold; affiliation reflects the publication record and does not necessarily indicate current employment.
Research Areas
Clinical Diagnostics and Health Records
Artificial intelligence is being investigated as a tool for veterinary diagnosis, quantitative pathology, and clinical information management. Applications include diagnostic classifiers, analysis of feline intestinal biopsies, thermal-image classification of canine tumors, and integration of machine learning into electronic health records. Studies also examine model reliability and reproducibility to understand how these tools could support veterinary care.
- Clinical Diagnostics and Health Records Publications
- 2026
Tumor-Specific Classification of Canine Cutaneous and Subcutaneous Tumors Using Heat-Diffusion Imaging and Artificial Intelligence
Gillian Dank, Tali Buber, Liron Levy-Hirsh, Michael S. Kent, Uri Greenberg, Yael Harpaz, Erez Hanael
2026
The influence, promise, and potential perils of artificial intelligence in veterinary medicine: a call for improved awareness and literacy
Francois-Rene Bertin, Jessica Lawrence, Stijn J M Niessen, Christopher J Pinard, Krystle L Reagan, Virginia Rentko
2026
The use of, and attitudes toward, artificial intelligence in members of the American College of Veterinary Internal Medicine and the European College of Veterinary Internal Medicine - Companion Animals
Francois-Rene Bertin, Jessica Lawrence, Stijn J M Niessen, Christopher J Pinard, Krystle L Reagan, Virginia Rentko
2025
Anna: an open-source platform for real-time integration of machine learning classifiers with veterinary electronic health records
Chun Yin Kong, Picasso Vasquez, Makan Farhoodimoghadam, Chris Brandt, Titus C. Brown, Krystle L. Reagan, Allison Zwingenberger & Stefan M. Keller
2025
Artificial intelligence-based quantification of lymphocytes in feline small intestinal biopsies
Judit M. Wulcan, Paula R. Giaretta, Sai Fingerhood, Simone de Brot, Esther E. V. Crouch, Tatiana Wolf, Maria Isabel Casanova, Pedro R. Ruivo, Pompei Bolfa, Nicolás Streitenberger, Christof A. Bertram, Taryn A. Donovan, Michael Kevin Keel, Peter F. Moore and Stefan M. Keller
2024
Diagnosis and classification of portosystemic shunts: a machine learning retrospective case-control study
Makan Farhoodimoghadam, Krystle L. Reagan, Allison L. Zwingenberger
2024
Classification performance and reproducibility of GPT-4 omni for information extraction from veterinary electronic health records
Judit M. Wulcan, Kevin L. Jacques, Mary Ann Lee, Samantha L. Kovacs, Nicole Dausend, Lauren E. Prince, Jonatan Wulcan, Sina Marsilio, Stefan M. Keller
2022
Evaluation of a machine learning tool to screen for hypoadrenocorticism in dogs presenting to a teaching hospital
Krystle L. Reagan, Jully Pires, Nina Quach, Chen Gilor
2021
Classification of neoplastic and inflammatory brain disease using MRI texture analysis in 119 dogs
Mason W. Wanamaker, Karen M. Vernau, Sandra L. Taylor, Derek D. Cissell, Yasser G. Abdelhafez, Allison L. Zwingenberger
2021
Diagnosis of Wilson Disease and Its Phenotypes by Using Artificial Intelligence
Valentina Medici, Anna Czlonkowska, Tomasz Litwin and Cecilia Giulivi
2020
Machine learning algorithm as a diagnostic tool for hypoadrenocorticism in dogs
K.L. Reagan, B.A. Reagan, C. Gilor
Disease Surveillance and One Health
Machine learning can help investigate disease risks across wildlife, livestock, humans, and shared environments. WSVM studies include predicting viral host associations and zoonotic potential, modeling climate-related changes in spillover risk, analyzing equine disease outbreaks, and combining receptor-binding experiments with computational prediction. Other work uses natural language processing to classify wildlife clinical records and support early detection of unusual illness and mortality events.
- Disease Surveillance and One Health Publications
- 2026
Climate-driven changes in zoonotic risk of arenaviral hemorrhagic fevers in South America
Pranav S. Kulkarni, Nuri Y. Flores-Pérez, Andie H. Jian, Brian H. Bird, Christine K. Johnson, Marcela Uhart, Pranav S. Pandit
2025
Decoding the blueprint of receptor binding by filoviruses through large-scale binding assays and machine learning
Gorka Lasso, Michael Grodus, Estefania Valencia, Veronica DeJesus, Eliza Liang, Isabel Delwel, Rob H. Bortz III, Dmitry Lupyan, Hanna Y. Ehrlich, Adrian A. Castellanos, Andrea Gazzo, Heather L. Wells, Supaporn Wacharapluesadee, Alexandre Tremeau-Bravard, Janine F. R. Seetahal, Tom Hughes, Jimmy Lee, Mei-Ho Lee, Anna R. Sjodin, Marike Geldenhuys, Marinda Mortlock, Isamara Navarrete-Macias, Kirsten Gilardi, Michael R. Willig, Alessandra F. D. Nava, Elisabeth H. Loh, Makda Asrat, Tierra Smiley-Evans, Walter S. Magesa, Sijali Zikankuba, David Wolking, Gerardo Suzán, Rafael Ojeda-Flores, Christine V. F. Carrington, Ariful Islam, Jonathan H. Epstein, Wanda Markotter, Christine K. Johnson, Tracey Goldstein, Barbara A. Han, Jonna A. K. Mazet, Rohit K. Jangra, Kartik Chandran, Simon J. Anthony
2023
Infection prediction in swine populations with machine learning
Avishai Halev, Beatriz Martínez-López, Maria Clavijo, Carlos Gonzalez-Crespo, Jeonghoon Kim, Chao Huang, Seth Krantz, Rebecca Robbins, Xin Liu
2023
Predicting Escherichia coli levels in manure using machine learning in weeping wall and mechanical liquid solid separation systems
B. Dharmaveer Shetty, Noha Amaly, Bart C. Weimer, Pramod Pandey
2023
Impact of sensor data pre-processing strategies and selection of machine learning algorithm on the prediction of metritis events in dairy cattle
Gema Vidal, James Sharpnack, Pablo Pinedo, Ching Tsai, Amanda Renee Lee, Beatriz Martínez-López
2023
Comparative performance analysis of three machine learning algorithms applied to sensor data registered by a leg-attached accelerometer to predict metritis events in dairy cattle
Gema Vidal, James Sharpnack, Pablo Pinedo, I Ching Tsai, Amanda Renee Lee, Beatriz Martínez-López
2022
Predicting the potential for zoonotic transmission and host associations for novel viruses
P. S. Pandit, S. J. Anthony, T. Goldstein, K. J. Olival, M. M. Doyle, N. R. Gardner, B. Bird, W. Smith, D. Wolking, K. Gilardi, C. Monagin, T. Kelly, M. M. Uhart, J. H. Epstein, C. Machalaba, M. K. Rostal, P. Dawson, E. Hagan, A. Sullivan, H. Li, A. A. Chmura, A. Latinne, C. Lange, T. O’Rourke, S. Olson, L. Keatts, A. P. Mendoza, A. Perez, C. D. de Paula, D. Zimmerman, M. Valitutto, M. LeBreton, D. McIver, A. Islam, V. Duong, M. Mouiche, Z. Shi, P. Mulembakani, C. Kumakamba, M. Ali, N. Kebede, U. Tamoufe, S. Bel-Nono, A. Camara, J. Pamungkas, K. J. Coulibaly, E. Abu-Basha, J. Kamau, S. Silithammavong, J. Desmond, T. Hughes, E. Shiilegdamba, O. Aung, D. Karmacharya, J. Nziza, D. Ndiaye, A. Gbakima, Z. Sajali, S. Wacharapluesadee, E. A. Robles, B. Ssebide, G. Suzán, L. F. Aguirre, M. R. Solorio, T. N. Dhole, N. T. T. Nga, P. L. Hitchens, D. O. Joly, K. Saylors, A. Fine, S. Murray, W. B. Karesh, P. Daszak, J. A. K. Mazet, PREDICT Consortium, C. K. Johnson
2022
Identifying Associations in Minimum Inhibitory Concentration Values of Escherichia coli Samples Obtained From Weaned Dairy Heifers in California Using Bayesian Network Analysis
Brittany L. Morgan, Sarah Depenbrock, Beatriz Martinez-Lopez
2022
Spatio-temporal PRRS epidemic forecasting via factorized deep generative modeling
Mohammadsadegh Shamsabardeh, Bahar Azari, Beatriz Martínez-López
2021
Early detection of wildlife morbidity and mortality through an event-based surveillance system
Terra R. Kelly, Pranav S. Pandit, Nicole Carion, Devin F. Dombrowski, Krysta H. Rogers, Stella C. McMillin, Deana L. Clifford, Anthony Riberi, Michael H. Ziccardi, Erica L. Donnelly-Greenan, Christine K. Johnson
2020
Biological Machine Learning Combined with Campylobacter Population Genomics Reveals Virulence Gene Allelic Variants Cause Disease
DJ Darwin R. Bandoy, Bart C. Weimer
Microbiomes and Agricultural Systems
Research in livestock and agricultural systems connects machine learning with animal health, microbiome science, pathogen genomics, and environmental monitoring. Examples include examining how rumen microbiomes relate to feed efficiency, reassessing diagnostic measurements for calf infections, and identifying dairy-management factors associated with antimicrobial resistance. Additional applications investigate bacterial host associations and estimate dairy-farm wastewater turbidity from images.
- Microbiomes and Agricultural Systems Publications
- 2026
Rethinking navel size thresholds for omphalitis diagnosis in newborn dairy calves using machine learning
A. Rico, A.F.A. Pires, N. Silva-del-Rio
2026
Genomic diversity and host-specificity in Corynebacterium pseudotuberculosis using comparative population genomics
Rodrigo Profeta, Cory L. Schlesener, Claire A. Shaw, Roselle C. Busch, Meera C. Heller, Sharon Spier, Jing Wu, Shannara Welch, Marcus Vinicius C. Viana, Fernanda A. L. Barroso, Bertram Brenig, Vasco Azevedo, Bart C. Weimer
2026
CNN-Based Turbidity Estimation in Dairy Farms Environments
Conference contribution. Abdullah Al Rawi, Behrooz Pakzadeh, Pramod Pandey
2024
An artificial intelligence approach of feature engineering and ensemble methods depicts the rumen microbiome contribution to feed efficiency in dairy cows
Hugo F. Monteiro, Caio C. Figueiredo, Bruna Mion, José Eduardo P. Santos, Rafael S. Bisinotto, Francisco Peñagaricano, Eduardo S. Ribeiro, Mariana N. Marinho, Roney Zimpel, Ana Carolina da Silva, Adeoye Oyebade, Richard R. Lobo, Wilson M. Coelho Jr, Phillip M. G. Peixoto, Maria B. Ugarte Marin, Sebastian G. Umaña-Sedó, Tomás D. G. Rojas, Modesto Elvir-Hernandez, Flávio S. Schenkel, Bart C. Weimer, C. Titus Brown, Ermias Kebreab & Fábio S. Lima
2021
Integration of statistical inferences and machine learning algorithms for prediction of metritis cure in dairy cows
E.B. de Oliveira, F.C. Ferreira, K.N. Galvão, J. Youn, I. Tagkopoulos, N. Silva-del-Rio, R.V.V. Pereira, V.S. Machado, F.S. Lima
2021
Dairy management practices associated with multi-drug resistant fecal commensals and Salmonella in cull cows: a machine learning approach
Pranav S. Pandit, Deniece R. Williams, Paul Rossitto, John M. Adaska, Richard Pereira, Terry W. Lehenbauer, Barbara A. Byrne, Xunde Li, Edward R. Atwill, Sharif S. Aly
2021
Large-Scale Data Mining of Rapid Residue Detection Assay Data From HTML and PDF Documents: Improving Data Access and Visualization for Veterinarians
Majid Jaberi-Douraki, Soudabeh Taghian Dinani, Nuwan Indika Millagaha Gedara, Xuan Xu, Emily Richards, Fiona Maunsell, Nader Zad, Lisa A. Tell
Imaging and Computational Analysis
Medical images and microscopy provide opportunities to identify patterns and measure biological features using computational methods. Applications at WSVM include deep-learning segmentation of equine PET scans, radiomics analysis of bone fractures and brain disease, and three-dimensional cellular segmentation. Related work combines brain imaging with mitochondrial measurements to investigate neurological disease and develop predictive models.
- Imaging and Computational Analysis Publications
- 2026
Deep learning cascade networks for segmentation of fluorine-18 sodium fluoride positron emission tomography scans of equine metacarpo- and metatarsophalangeal joints outperform atlas-based method
Sergey Anishchenko, Kathryn W. Bills, David Beylin, Natalie Beylin, Danielle Beylin, Karina Stepanova, Pavel Stepanov, Mathieu Spriet
2024
PrestoCell: A persistence-based clustering approach for rapid and robust segmentation of cellular morphology in three-dimensional data
Yue Wu, Ingrid Brust-Mascher, Melanie G. Gareau, Jesus A. De Loera, Colin Reardon
2023
Artificial Intelligence in Radiation Oncology
Seong K Mun and Sonja Dieterich
2022
Artificial neural network applied to fragile X-associated tremor/ataxia syndrome stage diagnosis based on peripheral mitochondrial bioenergetics and brain imaging outcomes
Cecilia Giulivi, Jun Yi Wang & Randi J. Hagerman
2022
Radiomics Modeling of Catastrophic Proximal Sesamoid Bone Fractures in Thoroughbred Racehorses Using μCT
Parminder S. Basran, Sean McDonough, Scott Palmer and Heidi L. Reesink
Drug Modeling and Food Safety
Predicting how drugs behave across animal species is a growing application of machine learning and chemical language models. Recent studies involving WSVM authors address plasma and tissue half-lives, drug-residue depletion, and clearance, alongside tools that improve access to regulatory and residue-testing data. These approaches support pharmacology and food-safety research, with further validation needed before predictions can inform clinical or regulatory decisions.
- Drug Modeling and Food Safety Publications
- 2026
A unified multi-task transformer framework for predicting drug half-lives in plasma and tissues across six food-producing species
Zhicheng Zhang, Lisa A. Tell, Zhoumeng Lin
2026
A Machine Learning-Empowered Quantitative Structure–Activity Relationship Model for Predicting the Plasma Half-life of Drugs in Dogs
Xue Wu, Pei-Yu Wu, Wei-Chun Chou, Lisa A. Tell, Zhoumeng Lin
2026
Development of Machine Learning and Chemical Language Model-Based QSAR Models for Predicting Drug Residue Depletion Half-Lives in Plasma and Tissues of Cattle Across Various Administration Routes
Zhicheng Zhang, Lisa A. Tell, Zhoumeng Lin
2026
Machine learning-based unified models for predicting drug clearance from pharmacokinetic animal and study design variables
Remya Ampadi Ramachandran, Lisa A. Tell, Melissa A. Mercer, Xuan Xu, Nuwan Indika Millagaha Gedara, Maaike Ottoline Clapham, Zhoumeng Lin, Jim E. Riviere, Majid Jaberi-Douraki
2021
Large-Scale Data Mining of Rapid Residue Detection Assay Data From HTML and PDF Documents: Improving Data Access and Visualization for Veterinarians
Majid Jaberi-Douraki, Soudabeh Taghian Dinani, Nuwan Indika Millagaha Gedara, Xuan Xu, Emily Richards, Fiona Maunsell, Nader Zad, Lisa A. Tell
Responsible AI and Research Tools
Reliable AI use requires attention to reproducibility, human oversight, and the needs of veterinary professionals. Studies evaluate large language models for extracting information from veterinary records and screening animal-health literature, while surveys examine AI literacy and use among students and specialists. This work helps identify useful applications, limitations, and training needs for responsible adoption in veterinary medicine and research.
- Responsible AI and Research Tools Publications
- 2026
A rule-based large language model screening framework for evidence synthesis in animal health: Feasibility evaluation in a veterinary scoping review
Christian Bernal-Córdoba, Ainhoa Valldecabres, Manuel Borona-Valencia, Oliver Canales-Muñoz, N. Silva-del-Río
2025
Veterinary students exhibit low artificial intelligence literacy but agree it will be deployed to improve veterinary medicine
Krystle L. Reagan, Karen Boudreaux, Stefan M. Keller
2024
Editorial: Revolutionizing life sciences: the nobel leap in artificial intelligence-driven biomodeling
Valentina Tozzini, Cecilia Giulivi
2020
Data challenges and practical aspects of machine learning-based statistical methods for the analyses of poultry data to improve food safety and production efficiency
Maurice Pitesky, Joseph Gendreau, Tristan Bond, Roberto Carrasco-Medanic